Spravato treatment centres in Spain — full list (4 centres, updated August 2026)

Spain has 4 registry-verified Spravato (esketamine) treatment centres — in L'Hospitalet de Llobregat (Barcelona), Barcelona, Sevilla and Dos Hermanas (Sevilla). Every centre is listed below with its access route, reimbursement note and the source it was verified against. Europe-wide picture: certified Spravato centres in Europe.

Certified centers administering esketamine nasal spray for treatment-resistant depression under medical supervision, usually within reimbursement programs.

Hospital-route model

Spravato®Registry-verified

Hospital Universitari de Bellvitge — Unidad de Depresión Resistente

L'Hospitalet de Llobregat (Barcelona), Spain
Esketamine nasal spray (Spravato®) · Repetitive TMS (rTMS)
Spravato®Registry-verified

Hospital Clínic Barcelona — Unidad de Trastornos Bipolares y Depresivos

Barcelona, Spain
Esketamine nasal spray (Spravato®) · Electroconvulsive therapy (ECT)
Spravato®Registry-verified

IASC — Instituto Andaluz de Salud Cerebral, Unidad de Terapia con Esketamina

Sevilla, Spain
Esketamine nasal spray (Spravato®) · IV ketamine
Spravato®Registry-verified

SAMU Wellness — Centro de Salud Mental, terapia con esketamina intranasal

Dos Hermanas (Sevilla), Spain
Esketamine nasal spray (Spravato®) · Repetitive TMS (rTMS)

Costs and coverage in Spain

  • Public fundingYes (hospital medicine, since 11/2022)
    ages 18–74; ≥3 failed strategies incl. augmentation
  • Worth knowingThe hospital psychiatry and pharmacy commission is the gatekeeper, and practice varies noticeably by region.
  • WhereL'Hospitalet de Llobregat (Barcelona), Barcelona, Sevilla, Dos Hermanas (Sevilla)
  • Access routesreferral from adult mental health centres (CSMA) / hospital psychiatric centres in the territory; self-administered nasal spray in hospital under medical and nursing supervision, ~90 minutes observation afterwards, referral from primary care centres (CAP) of Esquerra de l'Eixample, from the Clínic psychiatric emergency service, or on discharge after inpatient stay for patients registered with the mental health centre; specialised treatments assessed case by case, self-referral, psychiatric prescription and informed consent required; pre-treatment ECG; induction 2 sessions/week for 4 weeks, maintenance 1/week weeks 5–8, then individualised; ~1 hour supervision post-dose; patient must be accompanied and not drive, psychiatric assessment + medical assessment, then 6-month programme: induction 2x/week for 4 weeks, weeks 5–8 weekly, weeks 9–23 fortnightly; ~1 hour supervised observation, responsible physician on site

Prices are published by providers themselves, no estimates. Full picture: the European Price Index and the reimbursement map.