Spravato®Registry-verifiedDesignated-centers model

Psychiatrische Universitätsklinik Zürich (PUK)

Zürich, Switzerland

Treatment & access

  • Treatments offeredEsketamine nasal spray (Spravato®)
  • Access routeCovered by a national programme
  • Cost & coverage (registry status)Reimbursed by mandatory health insurance (OKP/AOS) per SL Limitatio
  • ReimbursementBAG Spezialitätenliste Limitatio: cantonal psychiatric care mandate required; list valid 2025-10-01 to 2028-09-30 How reimbursement works in Europe →
  • Phone+41 58 384 20 00
  • Websitehttps://www.pukzh.ch

Related listings

These records belong to the same organisation. They are listed separately because each is a distinct programme or location.

About this provider

The Psychiatric University Hospital Zurich (PUK) runs a dedicated ketamine and S-ketamine treatment service within its Ambulatorium Second Opinion Depression, aimed at people whose depression has not responded to at least two adequate treatment attempts in the current episode. PUK offers time-limited treatment with the approved S-ketamine nasal spray (Spravato) or racemic ketamine where indicated, alongside second-opinion assessments, electroconvulsive therapy and a psilocybin-assisted therapy programme. Registration for the specialised depression consultation is by email with a referral letter from a specialist physician.

Services & programs

  • Ambulatorium Second Opinion Depression: assessment and second opinions for treatment-resistant depression
  • Time-limited treatment with S-ketamine nasal spray (Spravato) or racemic ketamine where indicated
  • Electroconvulsive therapy (ECT) outpatient service
  • Psilocybin-assisted therapy programme within the depression focus area
  • Search for causes of treatment failure across biological, pharmacological and psychotherapeutic domains
  • Registration by email with a specialist referral letter

Programs & studies

ProgramKindStatus
S-ketamine (Spravato) treatment
PUK describes Spravato as the approved preparation; prior cost approval from the health insurer is required before treatment.
esketamine_nasaloffered
Racemic ketamine treatment
Offered alongside S-ketamine for treatment-resistant depression; costs may under certain circumstances be covered by the insurer.
ketamineoffered

Pricing

ItemPrice
Ketamine / S-ketamine treatment
PUK states costs may be covered by the health insurer less franchise and deductible; S-ketamine requires prior insurer cost approval, which the clinic can help arrange.
Not published

Prices are taken from the provider's own website and were last checked on . Always confirm the current price with the provider before booking.

Facilities & languages

  • LanguagesProvider website is published in German.
  • TeamThe treatment team consists of psychiatrists and nursing professionals; the clinic also trains staff from medical, nursing and therapeutic fields who are integrated into the treatment team.

Common questions

Who qualifies for ketamine or S-ketamine treatment at PUK?

The service targets patients with treatment-resistant depression, defined by PUK as at least two unsuccessful adequate treatment attempts in the current episode. For OKP-reimbursed Spravato, the Swiss Limitatio additionally requires age 18-74, failure of at least two antidepressants plus one augmentation attempt, CGI-S of 5 or higher, prior insurer approval (Kostengutsprache) and a 10-month maximum.

How do I register for the depression second-opinion service?

Registration is exclusively by email, and PUK requests a referral letter from a specialist physician. The clinic then assesses whether specialised options such as S-ketamine, ECT or other procedures could improve your situation.

Is treatment at PUK time-limited?

Yes. PUK describes its ketamine and S-ketamine offer as a time-limited treatment provided when appropriately indicated, which is consistent with the Swiss reimbursement limit of a maximum of 10 months of Spravato therapy.

Looking at alternatives? One of the BAG-designated Spravato centers; see the country guide and the limited-medical-use PAT program.

33 more verified providers within 50 km

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How to apply

Application route confirmed with the provider on 2026-09-29 (provider reply to psyaccess outreach).

Registration runs via the ZDAP form (Anmeldeformular ZDAP), completed and sent by your outpatient treating doctor, not by you or by us. Psilocybin-assisted therapy requires at least two different antidepressants plus one augmentation failed in the current episode, and runs only under an individual BAG authorisation (not guaranteed). Waitlist around 12 weeks. secondopiniondepression@pukzh.ch · Languages: German, English

Check your fit & enquire

Check my fit & enquire

Free 2-minute pre-screening in your browser · your summary goes only to Psychiatrische Universitätsklinik Zürich (PUK), with your consent.

What to prepare before you enquire

  • A referral or the contact details of your treating clinician
  • A list of medications you have tried (names, doses, duration)
  • A short diagnosis summary or discharge letters

Esketamine programmes usually require a documented history of antidepressant treatment.

Send documents directly to the provider when they reply. We never ask you to upload medical records.