Spravato®Registry-verifiedDesignated-centers model

GGZ Rivierduinen

Leiden, Netherlands

Treatment & access

Treatments offeredEsketamine nasal spray (Spravato®)
Access routeCovered by a national programme
Cost & coverage (registry status)Reimbursed via Dutch basic health insurance (esketamine nasal spray for TRD)
ReimbursementMember of Esketamine Neusspray Consortium (ENC-NL); esketamine covered per ENC-NL protocol How reimbursement works in Europe →
Websitehttps://www.rivierduinen.nl/

About this provider

GGZ Rivierduinen, a regional mental health institution in the Leiden area, started esketamine treatments in 2025 at its new esketamine outpatient clinic in Leiden. The treatment is intended for adults struggling with depression for whom other medication or therapies do not help sufficiently. During a session the esketamine is sprayed three times into both nostrils; clients describe an intense altered experience for roughly forty minutes and remain at the clinic until the effects subside, going home after about two hours. The total treatment lasts on average three to six months and consists of three phases. How quickly the medication takes effect differs per client.

Services & programs

Esketamine nasal spray treatment for adults with depression insufficiently helped by other medication or therapies, at the esketamine outpatient clinic in Leiden (since 2025)

Common questions

Who is the esketamine treatment for?

Adults who struggle with depression and for whom other medication or therapies do not help sufficiently.

What happens during a treatment session?

The medication is sprayed three times into both nostrils. The experience can feel intense for about forty minutes, with heightened senses; clients rest in a reclining chair in the treatment room and may go home after about two hours, when the intense feeling has decreased.

How long does the whole treatment take?

On average the total treatment lasts three to six months and consists of three phases. How quickly the medication takes effect differs per client.

Looking at alternatives? Esketamine nasal spray treatment is offered by specialised centres across the Netherlands affiliated with the national Esketamine Nasal Spray Consortium (ENC-NL), which lists GGZ Rivierduinen among its affiliated institutions.

13 more verified providers within 50 km

Alphen aan den Rijn · 11 kmSanctuary Kliniek : Spravato®
Den Haag · 15 kmPsyQ : Spravato®
Delft · 20 kmGGZ Delfland : Spravato®

See them on the provider map →

Verification

License / registryLRZa (Landelijk Register Zorgaanbieders, CIBG) — Stichting Rivierduinen, KvK 28103824; ENC-NL esketamine network member
Official registryhttps://zoeken.zorgaanbiedersportaal.nl/zorgaanbieder/Stichting%20Rivierduinen/28103824
Provider websitehttps://www.rivierduinen.nl/
Independent sourcehttps://enc-nl.nl/
Last verified2026-08-02

Re-checked every 90 days · how we verify and report corrections

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What to prepare before you enquire

A referral or the contact details of your treating clinician
A list of medications you have tried (names, doses, duration)
A short diagnosis summary or discharge letters

Esketamine programmes usually require a documented history of antidepressant treatment.

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