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Mondriaan

Heerlen, Netherlands

Treatment & access

About this provider

Mondriaan is the specialist mental health institution for South Limburg, headquartered in Heerlen (J.F. Kennedylaan 301). It offers esketamine nasal spray as an add-on to an oral antidepressant for depression in which three earlier medication steps failed: at least two different antidepressants plus an augmentation strategy such as lithium, mirtazapine or an antipsychotic gave no or insufficient improvement. The treatment is organised as day care: patients spend a half day or day at Mondriaan's day hospital in Maastricht and self-administer the spray with a pump device. The schedule runs from twice weekly (4 weeks) via weekly sessions to a maintenance phase of once a week down to once every three weeks; coordination runs via the treating psychiatrist (088 506 9260).

Services & programs

  • Esketamine nasal spray as add-on to a continued oral antidepressant for depression after three failed medication steps (two antidepressants plus an augmentation such as lithium, mirtazapine or an antipsychotic)
  • Day-treatment setting: sessions take place during a (half) day at Mondriaan's day hospital in Maastricht, with self-administration of the spray
  • Phased schedule: initiation 2 sessions per week for 4 weeks; on sufficient response an optimisation phase of 1 session per week for 4 weeks; then a maintenance phase reduced to between once a week and once every 3 weeks
  • Broader depression care programme within Mondriaan's adult mental health services

Common questions

Who qualifies for esketamine at Mondriaan?

People whose depression did not improve (enough) after three treatment steps: at least two different antidepressants and an add-on strategy such as lithium, mirtazapine or an antipsychotic. You keep taking an antidepressant during the esketamine treatment.

What does a session look like?

You spend a half day or day at the day hospital in Maastricht and administer the esketamine yourself with a nasal spray pump, similar to a regular nasal spray.

How long does the treatment take?

First 4 weeks with 2 sessions per week; with sufficient response 4 more weeks at 1 session per week, after which the frequency is reduced to a maintenance level between once a week and once every 3 weeks.

How is the treatment arranged?

Coordination runs via the treating psychiatrist; the esketamine coordination team is reachable on 088 506 9260.

Looking at alternatives? Other ENC-NL consortium centers across the Netherlands provide the same publicly reimbursed esketamine treatment; private routes are rare.

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Practical details

As stated on the provider's own website (checked 2026-09-09); details can change — confirm when you book.

  • BookingReferral required — the provider states access runs via a clinician's referral. Source →

Verification

Re-checked every 90 days · how we verify and report corrections

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Free 2-minute pre-screening in your browser · your summary goes only to Mondriaan, with your consent.

What to prepare before you enquire

  • A referral or the contact details of your treating clinician
  • A list of medications you have tried (names, doses, duration)
  • A short diagnosis summary or discharge letters

Esketamine programmes usually require a documented history of antidepressant treatment.

Send documents directly to the provider when they reply. We never ask you to upload medical records.

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