The Clinic of Change
Lisbon, Portugal
Treatment & access
- Treatments offeredKetamine-assisted psychotherapy (KAP) · Esketamine (Spravato) treatment for treatment-resistant depression · Psychiatry consultations · Clinical psychology · Psychotherapy (including cognitive-behavioural therapy and psychoanalytic approaches) · Child and adolescent psychiatry (ages 0-17) · Neuropsychological assessment · Anesthesiology assessment (pre-ketamine safety evaluation) · Family therapy · Couples therapy · Alcohol addiction treatment and relapse prevention · Treatment of depression, treatment-resistant depression, anxiety, burnout, PTSD, eating disorders · Treatment of behavioural addictions (gambling disorder, sex addiction) · Treatment of sexual dysfunctions
- Access routePrivate / self-funded
- Pricing (published by the provider)Per the clinic's website: the initial evaluation consultation costs 120€; the Ketamine-Assisted Psychotherapy (KAP) programme costs 3,900€ for patients with insurance and 5,500€ without insurance, both payable in four instalments.: as published, checked 2026-07-27
- Phone+351 218 071 715
- Websitehttps://theclinicofchange.com
Languages spoken
As stated by the provider on its own website: each language links to the exact page and wording it was verified against.
About this provider
The Clinic of Change is a private mental-health clinic in central Lisbon that opened in June 2023 as the first clinic in Portugal to offer a ketamine-assisted psychotherapy programme built on the Awakn Life Sciences clinical protocol; since June 2025 it follows its own methodology and reports more than 100 successfully treated cases in two years. It combines psychiatry, psychology, psychotherapy, child psychiatry and neuropsychological assessment with three medication-assisted programmes: Change KAP (8 weeks), Change KARE for alcohol relapse prevention (4 weeks) and an esketamine (Spravato) programme for treatment-resistant depression. The clinic is registered with the Portuguese health regulator ERS and is open every day, 8:30-20:00.
Services & programs
- Change KAP programme (ketamine-assisted psychotherapy)8-week programme combining supervised off-label intramuscular ketamine with specialised psychotherapy for treatment-resistant depression, anxiety, PTSD, eating disorders and addiction; 11 psychotherapy sessions and 4 ketamine administration sessions, with 18.5 hours of direct care and follow-ups at 3, 6, 9 and 12 months. 3,900€ with insurance / 5,500€ without insurance, divided into four payments
- Change KARE programme (alcohol relapse prevention)Intensive 4-week ketamine-assisted psychotherapy programme to consolidate sobriety and reduce alcohol relapse risk; 7 sessions in total, including 3 off-label ketamine sessions and therapeutic integration sessions. Not published
- Esketamine (Spravato) programmeNasal-spray esketamine for adults with treatment-resistant depression (non-response to at least two full antidepressant treatments), administered under medical supervision; also used in urgent situations such as severe depressive episodes with suicidal ideation due to its rapid action (1-4 weeks). Not published
- Initial medical evaluation1.5-hour assessment with a specialist psychiatrist to determine eligibility for the programmes; if the patient is eligible, the fee is credited against the first programme payment. 120€
- Psychiatry consultationsDiagnosis, treatment and monitoring of psychiatric conditions such as depression, anxiety, pathological grief, bipolar disorder and psychotic disorders, with individualised biopsychosocial treatment plans. Not published
- Psychology and psychotherapyClinical psychology, individual psychotherapy (psychoanalysis, CBT and other approaches), family therapy and couples therapy. Not published
- Child and adolescent psychiatryConsultations with child psychiatrists for emotional, behavioural and neurodevelopmental difficulties (anxiety, ADHD, autism spectrum) from birth to age 17. Not published
- Neuropsychological assessmentDetailed examination of cognitive, emotional and behavioural functioning for children, adolescents and adults, with a final report and recommendations. Not published
- Anesthesiology assessmentComplementary safety evaluation before ketamine treatment for patients with complex cardiac, respiratory, neurological or allergy conditions. Not published
Programs & studies
| Program | Kind | Status |
|---|---|---|
| Change KAP | Ketamine-assisted psychotherapy programme | Available |
| Change KARE | Alcohol relapse prevention programme | Available |
| Change Esketamine (Spravato) | Esketamine programme for treatment-resistant depression | Available |
Pricing
| Item | Price |
|---|---|
| KAP programme (patients with insurance) | 3,900€ |
| KAP programme (patients without insurance) | 5,500€ |
| Initial evaluation consultation | 120€ |
Facilities & languages
- Facilities
- Rua Picoas 12-R/C, 1050-173 Lisboa, Portugal
- Open daily 8:30-20:00, including Saturdays and Sundays
- Registered with the Portuguese Health Regulatory Authority (ERS): registration 39467, establishment E166508, operating licence 22863/2023
- Operated by Panegreen - Health and Wellness Solutions, LDA
- LanguagesWebsite available in Portuguese, English, French, Spanish, Chinese and Russian.
- TeamMultidisciplinary team of over 20 clinicians: psychiatrists, clinical psychologists and psychotherapists, a child and adolescent psychiatrist, neuropsychologists, an anesthesiologist and a research advisor. Clinical director Prof. Dr. Victor Amorim Rodrigues (psychiatrist, ISPA professor, former president of the Portuguese Federation of Psychotherapy). The team was trained on the Awakn Life Sciences protocol and works under supervision from international specialists including David Nutt (Imperial College Centre for Psychedelic Research) and Celia Morgan (University of Exeter).
Common questions
How much does the ketamine-assisted psychotherapy programme cost and what is included?
The KAP programme costs 3,900€ for patients with insurance and 5,500€ for patients without insurance, both divided into four payments. The initial evaluation consultation costs a fixed 120€ and is credited against the first payment if the patient is eligible. The programme runs up to 8 weeks with 18.5 hours of direct care: a 1.5-hour initial medical evaluation with a psychiatrist, 7 hours of psychotherapy (2 preparation sessions, 4 integration sessions and a final session), 4 ketamine administration sessions under medical supervision (up to 10 hours), and follow-ups at 3, 6, 9 and 12 months.
Is treatment covered by health insurance?
The clinic has agreements with major health insurers, and patients may have access to co-payment for certain acts within the conditions of their policy; the KAP programme itself is priced lower for insured patients (3,900€ vs 5,500€). Patients are advised to contact the clinic or their insurer about covered services, reimbursement rates and the procedures needed to activate coverage.
Do I need a referral or prescription to start?
No medical referral or prescription is required. Anyone can apply for treatment, and each case is then rigorously assessed by the medical team, including a review of the clinical history. Appointments can be booked through the website, by phone (+351 218 071 715 / +351 935 786 510) or by email (geral@theclinicofchange.com).
How does a treatment session work?
Therapy sessions without medication last 60 minutes; ketamine sessions last two hours. Ketamine is given as an intramuscular injection in the deltoid by a doctor or nurse, at sub-anesthetic doses, with continuous monitoring. Patients fast beforehand, can remain at the clinic until they feel ready to leave, must not drive or operate machinery for the rest of the day, and must be accompanied home by a person named before treatment starts.
Who is eligible and what conditions are treated?
Adults with conditions resistant to conventional treatment, including major depression, generalized anxiety, PTSD, eating disorders and addiction (alcohol and other substances, gambling, sex). Eligibility is assessed by a specialist psychiatrist. Contraindications include uncontrolled hypertension, severe cardiovascular disease, active psychosis or schizophrenia, and severe liver problems.
3 more verified providers within 50 km
- Lisboa · 0 kmIrmãs Hospitaleiras — Unidade de Saúde de Lisboa, programa de cetamina em ambulatório : Ketamine / KAP
- Lisboa · 0 kmCentro Hospitalar Psiquiátrico de Lisboa (Hospital Júlio de Matos) — Unidade de Depressão Resistente : Ketamine / KAP
- Barreiro · 11 kmUnidade Local de Saúde do Arco Ribeirinho (ULSAR) — Departamento de Psiquiatria e Saúde Mental : Spravato®
Verification
- License / registryERS — SRER (Sistema de Registo de Estabelecimentos Regulados)
- Official registryhttps://www2.ers.pt/DMZ/Pesquisa/Pesquisa.aspx
- Provider websitehttps://theclinicofchange.com
- Last verified
Check your fit & enquire
Ketamine / KAP access in Portugal follows published criteria. A short pre-screening comes first, then your compiled summary goes to The Clinic of Change only with your explicit consent, and you can download it for yourself either way.
Why enquire via PsyAccess
- Pre-screening first. A 2-minute check in your browser shows which legal routes fit your situation, before you reach out to anyone.
- A structured enquiry. Your enquiry reaches the provider with a structured summary, so the clinic can reply quickly and to the point.
- Independent & free. Free for patients. We don't charge for enquiries, and no provider pays for placement.