Spravato®Registry-verifiedDesignated-centers model

Amphia Ziekenhuis

Breda, Netherlands

Treatment & access

About this provider

Amphia hospital in Breda offers esketamine nasal spray for severe depression when other treatments have proven insufficient, documented in the psychiatry department's patient folder. Patients administer the spray themselves in the presence of a nurse and then remain in hospital for at least two hours under close nursing observation. During treatment, blood pressure, temperature, pulse and oxygen saturation are measured regularly, and questionnaires are completed before and after each session to track effect and side effects. Patients attend fasting (three hours before treatment); side effects typically begin within minutes of administration, decrease within an hour and are generally gone after two hours.

Services & programs

  • Esketamine nasal spray treatment at the hospital psychiatry department
  • Nurse-supervised self-administration with at least two hours of monitored observation per session
  • Vital-signs monitoring during treatment: blood pressure, temperature, pulse and oxygen saturation
  • Questionnaire-based monitoring before and after treatment sessions

Common questions

What happens during a treatment session?

You spray the esketamine into your nose yourself in the presence of a nurse. Afterwards you stay in the hospital for at least two hours while a nurse keeps a close eye on you; your blood pressure, temperature, pulse and oxygen saturation are measured regularly, and questionnaires are completed around the session.

How should I prepare?

You must attend fasting: no food for three hours before the treatment.

What about side effects?

Side effects usually start within minutes after administration, decrease within one hour and are generally gone after two hours, which is why you remain under observation. Amphia's folder also warns that esketamine nasal spray can occasionally cause serious allergic symptoms (anaphylaxis) such as breathing problems, skin swelling and rash.

Looking at alternatives? In the wider region, Elisabeth-TweeSteden Ziekenhuis (Tilburg), Reinier van Arkel ('s-Hertogenbosch) and Emergis (Zeeland) are also ENC-NL esketamine centres. See enc-nl.nl and our Netherlands country guide.

7 more verified providers within 50 km

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Practical details

As stated on the provider's own website (checked 2026-09-09); details can change — confirm when you book.

  • Opening hoursPolikliniek Psychiatrie Mon-Fri 08:00-12:30 and 13:30-16:00 Source →
  • BookingReferral required — the provider states access runs via a clinician's referral. Source →

Verification

Re-checked every 90 days · how we verify and report corrections

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Free 2-minute pre-screening in your browser · your summary goes only to Amphia Ziekenhuis, with your consent.

What to prepare before you enquire

  • A referral or the contact details of your treating clinician
  • A list of medications you have tried (names, doses, duration)
  • A short diagnosis summary or discharge letters

Esketamine programmes usually require a documented history of antidepressant treatment.

Send documents directly to the provider when they reply. We never ask you to upload medical records.