PsyAccess
Spravato®Registry-verifiedDesignated-centers model

Psychiatrische Universitätsklinik Zürich (PUK)

Zürich, Switzerland

Treatment & access

  • Treatments offeredesketamine (Spravato)
  • Access routepublic_reimbursed
  • Price informationReimbursed by mandatory health insurance (OKP/AOS) per SL Limitatio
  • ReimbursementBAG Spezialitätenliste Limitatio: cantonal psychiatric care mandate required; list valid 2025-10-01 to 2028-09-30 How reimbursement works in Europe →
  • Phone+41 58 384 20 00
  • Websitehttps://www.pukzh.ch

About this provider

The Psychiatric University Hospital Zurich (PUK) runs a dedicated ketamine and S-ketamine treatment service within its Ambulatorium Second Opinion Depression, aimed at people whose depression has not responded to at least two adequate treatment attempts in the current episode. PUK offers time-limited treatment with the approved S-ketamine nasal spray (Spravato) or racemic ketamine where indicated, alongside second-opinion assessments, electroconvulsive therapy and a psilocybin-assisted therapy programme. Registration for the specialised depression consultation is by email with a referral letter from a specialist physician.

Services & programs

  • Ambulatorium Second Opinion Depression: assessment and second opinions for treatment-resistant depression
  • Time-limited treatment with S-ketamine nasal spray (Spravato) or racemic ketamine where indicated
  • Electroconvulsive therapy (ECT) outpatient service
  • Psilocybin-assisted therapy programme within the depression focus area
  • Search for causes of treatment failure across biological, pharmacological and psychotherapeutic domains
  • Registration by email with a specialist referral letter

Common questions

Who qualifies for ketamine or S-ketamine treatment at PUK?

The service targets patients with treatment-resistant depression, defined by PUK as at least two unsuccessful adequate treatment attempts in the current episode. For OKP-reimbursed Spravato, the Swiss Limitatio additionally requires age 18-74, failure of at least two antidepressants plus one augmentation attempt, CGI-S of 5 or higher, prior insurer approval (Kostengutsprache) and a 10-month maximum.

How do I register for the depression second-opinion service?

Registration is exclusively by email, and PUK requests a referral letter from a specialist physician. The clinic then assesses whether specialised options such as S-ketamine, ECT or other procedures could improve your situation.

Is treatment at PUK time-limited?

Yes. PUK describes its ketamine and S-ketamine offer as a time-limited treatment provided when appropriately indicated, which is consistent with the Swiss reimbursement limit of a maximum of 10 months of Spravato therapy.

Looking at alternatives? One of the BAG-designated Spravato centers; see the country guide and the limited-medical-use PAT program.

Verification

This record was taken directly from an official registry or program list and is re-checked on a rolling cadence.

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