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Ziekenhuisgroep Twente (ZGT)

Almelo / Hengelo, Netherlands

Treatment & access

About this provider

Ziekenhuisgroep Twente (ZGT) has operated an esketamine outpatient clinic within its psychiatry department since 1 July 2024 — the only hospital in the region with such a clinic and, per ZGT, the second largest in the Netherlands. The esketamine nasal spray is offered to people with difficult-to-treat depression for whom standard treatments yield insufficient results; only a small group of patients qualifies. In the first weeks patients come to the clinic twice a week, after which the frequency of maintenance treatments is assessed. Blood pressure and general health are closely monitored during treatments. ZGT states that when esketamine is used early in treatment according to protocol, symptoms clearly decrease in more than half of these patients. The department also offers ECT and vagus nerve stimulation.

Services & programs

  • Esketamine nasal spray treatment at the esketamine outpatient clinic, psychiatry department (since 1 July 2024)
  • Electroconvulsive therapy (ECT) for severe depression
  • Vagus nerve stimulation for patients not responding to other treatments
  • Inpatient psychiatry (37 beds), day treatment and expressive therapies (music, drama, art, psychomotor)

Common questions

Who qualifies for the esketamine treatment?

The treatment is for people with difficult-to-treat depression for whom the usual treatments yield insufficient results. Only a small group of patients qualifies; ZGT notes it works best when used early in treatment according to protocol.

How often do I come for treatment?

In the first weeks you come to the esketamine clinic twice a week for treatment. After that, it is assessed how often you need maintenance treatments.

How is safety monitored?

During the treatments your blood pressure and general health are always carefully monitored.

What results are seen?

ZGT states that in more than half of these patients, symptoms clearly decrease when esketamine is used early in treatment according to protocol.

Looking at alternatives? Esketamine nasal spray treatment is offered by specialised centres across the Netherlands affiliated with the national Esketamine Nasal Spray Consortium (ENC-NL); for treatment-resistant depression it has been reimbursed from the basic health insurance package since September 2021.

Verification

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