Ketamine / KAPPending re-verificationDesignated-centers model

Istituto di Neuroscienze

Florence, Italy

Treatment & access

  • Treatments offeredKetamine and esketamine (Spravato) for treatment-resistant depression · Intravenous (IV) infusion therapy · Transcranial Magnetic Stimulation (TMS), including rTMS, Theta-Burst (TBS), SNT and Deep TMS · tDCS and other neuromodulation therapies · Neurofeedback · Pharmacological therapy and psychotherapy combined with neuromodulation
  • Access routeprivate_pay
  • Price informationPer the clinic's website, individual service fees are not itemised; its online payment page lets patients pay preset amounts ranging from 30 EUR to 1002 EUR (including values such as 82 EUR, 92 EUR and 102 EUR) via PayPal, without mapping each amount to a named service.
  • Phone+39 055 587889
  • Websitehttps://istitutodineuroscienze.it

About this provider

The Istituto di Neuroscienze, founded in Florence in 1989 by Dr. Stefano Pallanti, is a clinical neuroscience centre offering treatment, wellness and prevention, with activity across Florence, Bologna, Milan and Monza. It combines a European phenomenological tradition with an evidence-based approach and applies the Pallanti Method of translational clinical neuroscience. Core therapies include neuromodulation via Transcranial Magnetic Stimulation (rTMS, Theta-Burst, SNT and Deep TMS) begun in 2005, and pharmacotherapy including ketamine infusion and intranasal esketamine (Spravato) for treatment-resistant depression, alongside intravenous infusion therapy. The institute treats conditions such as resistant depression, OCD, anxiety, behavioural addictions and cognitive disorders, and has a long history of research and early adoption of new treatments. It is located on Via Alfonso Lamarmora in Florence.

Services & programs

  • Ketamine and esketamine for treatment-resistant depressionKetamine is used in infusion therapy and esketamine (the S-ketamine, marketed as Spravato) is given intranasally; both are described as fast-acting in reducing symptoms of depression and suicidal ideation and are used following careful case selection in a controlled setting with long-term monitoring. Esketamine spray use began at the institute in 2021. Not published
  • Intravenous (IV) infusion therapyInfusion therapy for depression, OCD, anxiety and cognitive disorders, delivered in a Day-Center regime without hospitalisation, offering greater tolerability and generally faster response. Medications that can be administered by infusion include ketamine, citalopram, clomipramine, ademetionine, N-acetylcysteine, sodium valproate, levosulpiride, tiapride and secretin. Not published
  • Transcranial Magnetic Stimulation (TMS)Non-invasive, non-pharmacological neuromodulation offered as rTMS, Theta-Burst Stimulation (TBS), the multi-session SNT protocol, and Deep TMS, personalised per patient for conditions including resistant depression and OCD. The institute began rTMS in 2005. Not published
  • NeurofeedbackNeurofeedback, introduced for ADHD, among the institute's neuromodulation and diagnostic tools. Not published

Programs & studies

ProgramKindStatus
The Pallanti Method
A translational clinical neuroscience approach translating clinical symptoms into their functional meaning, combining respect for the person with cutting-edge techniques.
Clinical approachActive
Life-span ADHD program
Program for children and adults, running since 1992.
Clinical programActive
Behavioural addictions and pathological gambling program
Started in 1998; later incorporated rTMS in collaboration with Harvard University (2017).
Clinical programActive
PANDAS-PANS program
Program noted among the institute's specialised care pathways since 2001.
Clinical programActive

Pricing

ItemPrice
Online payment amounts (PayPal), not mapped to specific services
The payment page offers these selectable amounts to pay for services (prestazioni) but does not state which amount corresponds to which treatment.
Preset values from 30 EUR to 1002 EUR (e.g. 30, 40, 50, 70, 82, 92, 102, 152, 182, 202, 302, 402, 452, 482, 502, 602, 702, 782, 802, 902, 1002 EUR)

Prices are taken from the provider's own website and were last checked on . Always confirm the current price with the provider before booking.

Facilities & languages

  • Facilities
    • Main site: Via Alfonso Lamarmora 24, 50121 Florence
    • Activity also referenced in Bologna, Milan and Monza
    • Day-Center for assessments and infusion therapy without hospitalisation
  • LanguagesWebsite available in Italian and English.
  • TeamFounded and led by Dr. Stefano Pallanti, described as a physician-neuroscientist and a founding member of the Clinical TMS Society; the institute emphasises his research output and collaborations, including with Harvard University.

Common questions

How much do treatments cost and what is included?

Individual service fees are not itemised on the website. The online payment page allows patients to pay preset amounts ranging from 30 EUR to 1002 EUR via PayPal, MyBank or debit/credit card, but does not map each amount to a specific treatment.

Is treatment covered by the public health service or reimbursed?

The website does not state public (SSN) coverage; it presents payment as a private transaction handled securely through PayPal, and historically notes that Italy was the last European country to guarantee reimbursement for SSRI treatment of depression (from 2001), reflecting the institute's emphasis on offering validated innovations ahead of bureaucratic processes.

How do I get started or make contact?

You can call +39 055 587889, email info@istitutodineuroscienze.it, or complete the contact form on the site. The institute notes messages are read periodically, so replies may not be immediate.

What does a course of neuromodulation or infusion treatment involve?

TMS is delivered in personalised protocols (rTMS, Theta-Burst, the multi-session SNT protocol and Deep TMS) tailored to the patient's symptoms; the accelerated SNT protocol uses several daily sessions. IV infusion therapy is delivered in a Day-Center regime without hospitalisation.

Who is ketamine or esketamine treatment suitable for?

The institute states ketamine and esketamine are used for treatment-resistant depression, chosen after careful examination of each case, since both are hallucinogenic and require administration in a controlled setting with close, long-term monitoring.

Looking at alternatives? In Italy, esketamine (Spravato) is a Classe H medicine dispensed via hospital specialist settings.

Verification

This record was verified previously and is awaiting its scheduled re-check against the registry.

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