Ketamine / KAPPending re-verificationPrivate-market model

MainOP

Frankfurt am Main, Germany

Treatment & access

  • Treatments offeredKetamine infusion therapy (treatment-resistant depression, chronic pain incl. fibromyalgia, PTSD, OCD, anxiety disorders, addiction disorders, migraine)
  • Access routeprivate_pay
  • Price informationThe clinic's ketamine page states that a single ketamine infusion in Frankfurt costs on average €200 to €300, and that as an off-label treatment the costs are currently not covered by statutory health insurers, while some private insurers reimburse partially or fully (mainop.de/behandlungen/ketamin/).
  • Phone+49 6145 5458671
  • Websitehttps://mainop.de

About this provider

MainOP Klinik is a modern outpatient and short-stay clinic on the MainMED health campus in Flörsheim am Main near Frankfurt Airport, opened in 2024 with three operating theatres and up to ten beds. Alongside its surgical specialties (orthopaedics, spine, general and plastic surgery, ophthalmic surgery) and weight-loss procedures, it offers ketamine infusion therapy for treatment-resistant depression and chronic pain, as well as PTSD, obsessive-compulsive disorder, anxiety, addiction disorders and migraine. Infusions are given on an outpatient basis, last about 40 minutes and are supervised by an experienced anaesthetist with continuous monitoring; a typical course comprises three to eight infusions at one-to-two-day intervals, with repeat treatments possible depending on response.

Services & programs

  • Ketamine infusion therapyOutpatient intravenous ketamine infusion of about 40 minutes via venous cannula, with the patient reclining and monitored throughout by trained medical staff; every infusion is supervised by an experienced anaesthetist with individually adjusted dosing. A short recovery phase follows before the patient leaves. Indications listed: treatment-resistant depression, chronic pain (e.g. fibromyalgia), OCD, addiction disorders, anxiety disorders, PTSD and migraine. On average €200–300 per single infusion, as stated by the clinic
  • Outpatient and short-stay surgerySurgical services in ophthalmic surgery, orthopaedics, spine surgery, general surgery, plastic surgery, and anaesthesiology/pain therapy, in three modern operating theatres with up to ten beds for recovery. Not published; the clinic lists KV billing for outpatient operations, hybrid DRG, direct contracts with health insurers and DRG billing for private patients

Programs & studies

ProgramKindStatus
Ketamine infusion course
Usually three to eight infusions at intervals of one to two days, depending on severity and response; effect duration ranges from days to several months, and repeat infusions at regular intervals may be needed.
ketamine_ivactive

Pricing

ItemPrice
Single ketamine infusion
Average figure for Frankfurt stated on the clinic's ketamine page. Off-label use: not reimbursed by statutory (GKV) insurers per the clinic; some private insurers reimburse partially or fully — the clinic advises clarifying reimbursement in advance.
approx. €200–300

Prices are taken from the provider's own website and were last checked on . Always confirm the current price with the provider before booking.

Facilities & languages

  • Facilities
    • Three modern operating theatres
    • Up to ten beds for outpatient and short-stay care, plus recovery room
    • On-site sterile goods reprocessing unit (AEMP)
    • MainMED health campus of over 5,000 sqm with multiple medical practices under one roof
    • Location near Frankfurt Airport, reachable from Wiesbaden, Mainz and Darmstadt
  • LanguagesWebsite and patient information are provided in German.
  • TeamTeam of experienced physicians, nursing staff and specialized surgeons; every ketamine infusion is supervised by an experienced anaesthetist with continuous monitoring and individually adjusted dosing.

Common questions

What does a ketamine infusion cost and does insurance pay?

The clinic states an average of €200 to €300 per single infusion in Frankfurt. Because ketamine for depression is an off-label use, statutory health insurers currently do not reimburse it; some private insurers cover the costs partially or fully, and the clinic recommends clarifying this in advance.

How do I start treatment?

Contact the clinic directly by phone (+49 6145 5458671), email (info@mainop.de) or the online contact form linked from the ketamine page. A careful pre-examination is carried out first to rule out contraindications such as psychosis, cardiovascular disease or glaucoma.

Is the treatment inpatient or outpatient?

Ketamine infusions usually take place on an outpatient basis and last about 40 minutes, followed by a short recovery phase before leaving the clinic. The clinic also has up to ten beds for short-stay care.

What does the treatment involve and how does it feel?

The medication is administered slowly through a venous cannula while the patient lies relaxed and is continuously monitored. Many patients report a transient feeling of dissociation or light trance during the infusion, which subsides quickly afterwards. Typical courses are three to eight infusions at one-to-two-day intervals.

How long does the effect last?

Per the clinic, duration is very individual — from a few days to several months. Some patients have a lasting effect after a single infusion, while others need repeat infusions at regular intervals.

Looking at alternatives? In Germany, esketamine nasal spray is an approved, statutory-insurance-covered option for treatment-resistant depression at qualified psychiatric practices and hospitals; university and public psychiatric hospitals also run ketamine programmes, clinical trials recruit patients, and compassionate-use psilocybin exists in narrowly defined individual cases.

Verification

This record was verified previously and is awaiting its scheduled re-check against the registry.

  • License / registryPublic trial registry (ClinicalTrials.gov / EU CTIS)
  • Sourcehttps://mainop.de
  • Last verified

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